A new tool for reliable metabolic phenotyping of fish2018-06-05
Researchers from the Nutrigenomics and Fish Growth Endocrinology Group of the Institute of Aquaculture Torre de la Sal have evaluated the value of sirtuins (SIRTs), a family of proteins considered as master regulators of metabolism, for the metabolic phenotyping of the gilthead sea bream, a marine fish of high value for the Mediterranean aquaculture. The study showed that SIRTs may play different roles in the regulation of metabolism, inflammatory tone and growth in farmed fish. Also, the study revealed that the SIRTs profile allows the identification of individuals with metabolic features that lead to efficient and lean fish. This may be particularly useful in breeding programs for this species, by assisting gross measurements of visceral fat that are currently used to indirectly select efficient fish. The study has been published in Frontiers in Physiology and was founded by the projects MI2-Fish and PROMETEO FASE II, with additional support from PerformFISH-H2020.
Full reference: Paula Simó-Mirabet, Erick Perera, Josep Alvar Calduch-Giner, Juan Manuel Afonso, Jaume Pérez-Sánchez. Co-expression Analysis of Sirtuins and Related Metabolic Biomarkers in Juveniles of Gilthead Sea Bream (Sparus aurata) with Differences in Growth Performance. Front. Physiol. | doi: 10.3389/fphys.2018.00608.
